Call Now
(415) 798-9275
Edit Search
You must provide a location
Check In - Check Out
Rooms and Guests
2 Adults, 1 Room
Rooms
1
Adults
2
Children
0
Rooms must be less than number of adults
Children's ages must be provided
50 photos

Residence Inn Durham McPherson/Duke University Medical Cntr

1108 West Main Street, Durham, NC

Check In
06/28/2026
Check Out
06/29/2026
Rooms
1
1
2
3
4
5
6
7
8
9
Adults
2
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
Children
0
0
1
2
3
4
5
6
7
8
Enter children's ages (infant to 17 years):
Rooms must be less than number of adults
Children's ages must be provided
FIND ROOMS
Check In Date
Check Out Date

Have questions? We're here to help!

(415) 798-9275
Reservations Portal is an independent travel network. Learn More
Reasons to book with ReservationsPortal

As an independent travel network with access to over 100,000 hotels worldwide, we bring you the same great deals you'd find with major travel agencies or booking directly with hotels. By sourcing the best rates from top suppliers, we make it easy to find and book your ideal room. Our platform also features a seamless booking engine for all devices, a strong commitment to privacy, and exceptional customer support—delivering the complete Reservations Portal experience.

Room Options

Best Value!

1 Bedroom, Suite, Accessible

Check Rates
Room Details
1 Bedroom, Suite, Accessible

Studio, King Bed, Sofa, Accessible

Check Rates
Room Details
Studio, King Bed, Sofa, Accessible

Studio, Queen Bed, Sofa

View amenities and details
Check Rates
Room Details
Studio, Queen Bed, Sofa
Room Facilities
Air Conditioning
Desk/Workspace
Dishwasher
Hair Dryer
Iron/Ironing Board
Kitchen Facilities
Microwave Oven
Refrigerator
Stove
Tea And Coffee Making Facility
Television

Studio, King Bed, Sofa

Check Rates
Room Details
Studio, King Bed, Sofa

1 Bedroom, Suite

View amenities and details
Check Rates
Room Details
1 Bedroom, Suite
Room Facilities
Air Conditioning
Desk/Workspace
Dishwasher
Hair Dryer
Iron/Ironing Board
Kitchen Facilities
Microwave Oven
Refrigerator
Stove
Tea And Coffee Making Facility
Television

Suite, Multiple Beds, Accessible

Check Rates
Room Details
Suite, Multiple Beds, Accessible

Studio, King Bed

View amenities and details
Check Rates
Room Details
Studio, King Bed
Room Facilities
Air Conditioning
Desk/Workspace
Dishwasher
Hair Dryer
Iron/Ironing Board
Kitchen Facilities
Microwave Oven
Refrigerator
Stove
Tea And Coffee Making Facility
Television

1 Bedroom, Suite, Sofa, Accessible

Check Rates
Room Details
1 Bedroom, Suite, Sofa, Accessible

Studio, 1 King Bed With Sofa Bed (Mobility/Hearing Accessible, Tub)

Check Rates
Room Details
Studio, 1 King Bed With Sofa Bed (Mobility/Hearing Accessible, Tub)
Cancellation Rules
Limited Availability

Inventory is based on real-time data provided by our supply partners. Availability is strictly limited to the allotment provided to us and is subject to change.

24-Hour Free Cancellation

Residence Inn Durham McPherson/Duke University Medical Cntr Amenities

Dry cleaning/laundry service
Vegetarian breakfast available
Conference space size (meters) - 235
Free WiFi
Wheelchair accessible parking
LED light bulbs
Wheelchair-accessible lounge
Wheelchair-accessible on-site restaurant
Free breakfast
Number of accessible parking spaces - 7
Wheelchair-accessible meeting spaces/business center
Coffee/tea in common areas
Laundry facilities
Elevator
Fitness facilities
Wheelchair accessible (may have limitations)
Banquet hall
Assistive listening devices in meeting rooms
Wheelchair-accessible path to elevator
Wheelchair-accessible fitness center
Internet access in public areas - high speed
Wedding services
24-hour fitness facilities
Free area shuttle
Elevator door width (inches) - 42
Free breakfast to go
Elevator door width (centimeters) - 107
Water-efficient showers only
Luggage storage
Business center
24-hour front desk
Smoke-free property
Safe-deposit box at front desk
Conference space
Wheelchair accessible path of travel
Conference space size (feet) - 2530
Concierge services

Residence Inn Durham McPherson/Duke University Medical Cntr Hotel Details

Stay at the Residence Inn Durham McPherson/Duke University Medical Center, located in downtown Durham, within a 10-minute walk of Duke University and Brightleaf Square. This hotel is 10. 5 miles from the University of North Carolina and 0. 9 miles from the Durham Performing Arts Center. Enjoy a 24-hour fitness center, a terrace, complimentary Wi-Fi, concierge and wedding services, and a complimentary area shuttle. The 147 guestrooms feature kitchens with full-sized refrigerators/freezers and stovetops, 32-inch Smart TVs with cable, and complimentary Wi-Fi. Safes, desks, and phones with free local calls are also provided. A grocery/convenience store is available onsite. Unwind at the bar/lounge or enjoy a complimentary on-the-go breakfast served daily from 7:00 AM to 9:00 AM. The hotel offers a business center, express check-in/check-out, and 2, 530 square feet of event space. Self-parking is available (subject to charges).
Residence Inn Durham McPherson/Duke University Medical Cntr
1108 West Main Street, Durham, NC
Choose your dates to book today's available rooms and dates
Check In
06/28/2026
Check Out
06/29/2026
Rooms
1
Adults
2
Children
0
Rooms must be less than number of adults
Children's ages must be provided
FIND ROOMS
Check In Date
Check Out Date
Confirm Your Dates
You're about to search for rooms from to . Are these the correct dates for your stay?
Yes, find rooms Change dates

Securing your special rate...

SECURE ENCRYPTION ACTIVE
CHECK-IN
CHECK-OUT
RATE NOT GUARANTEED UNTIL BOOKED