VegasVacay is an independent travel network.
Edit Search
You must provide a location
Check In - Check Out
11/10/2026 - 11/11/2026
Rooms and Guests
2 Adults, 1 Room
Rooms
1
Adults
2
Children
0
Rooms must be less than number of adults
Children's ages must be provided
14 photos

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr, Sikeston, MO

Have questions? We're here to help!

(888) 450-6644
Check In - Check Out
Rooms
1
1
2
3
4
5
6
7
8
9
Adults
2
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
Children
0
0
1
2
3
4
5
6
7
8
Enter children's ages (infant to 17 years):
Rooms must be less than number of adults
Children's ages must be provided
Find Rooms
Reservations Portal is an independent travel network. Learn More
Reasons to book with ReservationsPortal

As an independent travel network with access to over 100,000 hotels worldwide, we bring you the same great deals you'd find with major travel agencies or booking directly with hotels. By sourcing the best rates from top suppliers, we make it easy to find and book your ideal room. Our platform also features a seamless booking engine for all devices, a strong commitment to privacy, and exceptional customer support—delivering the complete Reservations Portal experience.

Room Options

Select your dates to view available rooms and rates.

Best Value!

1 Bedroom, Suite, King Bed

1 Bedroom, Deluxe, Suite, King Bed

2 Bedrooms, Suite

1 Bedroom, Deluxe, Suite, Queen Bed

1 Bedroom, Suite, 2 Queen Beds

1 Bedroom, Deluxe, Suite, 2 Queen Beds

2 Bedrooms, Suite, 1 King And 2 Double Beds

Suite, King Bed

Suite, 2 Queen Beds

Limited Availability

Inventory is based on real-time data provided by our supply partners. Availability is strictly limited to the allotment provided to us and is subject to change.

24-Hour Free Cancellation

Days Inn and Suites by Wyndham Sikeston Amenities

Banquet hall
LED light bulbs
Free breakfast to go
Free RV, bus, truck parking
Luggage storage
Free breakfast
Coin laundry on site
Wheelchair-accessible path to elevator
Number of meeting rooms - 3
Meeting rooms
24-hour front desk
Free WiFi
Library
Smoke-free property
Internet access in public areas - high speed
Laundry facilities
Free self parking
Elevator
Fitness facilities

Policies

Check-in: 3:00 PM, minimum check-in age 18. Check-out: 11:00 AM

Days Inn and Suites by Wyndham Sikeston Hotel Details

Located in Days Inn & Suites by Wyndham Sikeston, this hotel is a perfect starting point from which to explore Sikeston, Missouri. Featuring a complete list of amenities, guests will find their stay at the property comfortable and convenient. Take advantage of the hotel’s Wi-Fi in public areas, car park, laundry service, elevator, and pet-friendly accommodations. This is a non-smoking property, ensuring a clean and fresh environment for all guests. Each guestroom is elegantly furnished and equipped with handy amenities. To enhance guests' stay, the hotel offers recreational facilities such as a fitness center. Friendly staff, great facilities, and close proximity to all that Sikeston has to offer are three great reasons you should stay at Days Inn & Suites by Wyndham.
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Choose your dates to see available rooms and rates
Check In
Check Out
Rooms
1
Adults
2
Children
0
Rooms must be less than number of adults
Children's ages must be provided
FIND ROOMS
Confirm Your Dates
You're about to search for rooms from to . Are these the correct dates for your stay?
Yes, find rooms Change dates

Check-in
-
Check-out