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11/11/2026 - 11/12/2026
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Comfort Inn & Suites Sikeston I-55

109 Matthews Ln, Sikeston, MO

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(888) 450-6644
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Comfort Inn & Suites Sikeston I-55 Amenities

Number of indoor pools - 1
Wheelchair accessible (may have limitations)
Safe-deposit box at front desk
Wheelchair accessible parking
Laundry facilities
Free self parking
Elevator
Fitness facilities
Business center
24-hour front desk
Free WiFi

Policies

Check-in: 2:00 PM, minimum check-in age 18. Check-out: 11:00 AM

Comfort Inn & Suites Sikeston I-55 Hotel Details

Enjoy a comfortable stay at the Comfort Inn & Suites Sikeston I-55, conveniently located within a 10-minute walk of The Book Bug and the City of Miner Convention Center. Our hotel offers an indoor pool and fitness center, perfect for unwinding after a day of exploring. Stay connected with complimentary Wi-Fi in our 64 air-conditioned guest rooms, each equipped with a coffee/tea maker and a private bathroom. Additional amenities include a business center, 24-hour front desk service, and laundry facilities. Free self-parking is available on-site. Nearby attractions include the Sikeston Depot Museum (3. 3 mi) and the Mississippi River (17. 6 mi). We are also a short drive from the Cape Girardeau Municipal Airport (CGI).
Comfort Inn & Suites Sikeston I-55
109 Matthews Ln, Sikeston, MO
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Rooms
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Adults
2
Children
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Rooms must be less than number of adults
Children's ages must be provided
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